IFNAR1

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
Clone#2A5B12
Entrez GenelD3454
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human IFNAR1 (AA: 28-156) expressed in E. Coli.
MW63.5kDa
Species ReactivityHuman, Mouse
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
extra(28-156)
Catalog#: 32364
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using IFNAR1 mAb against human IFNAR1 (AA: 28-156) recombinant protein. (Expected MW is 40.8 kDa)
Figure 2:Western blot analysis using IFNAR1 mAb against human IFNAR1 (AA: 28-156) recombinant protein. (Expected MW is 40.8 kDa)
Western Blot
Figure 3:Western blot analysis using IFNAR1 mAb against HEK293-6e (1) and IFNAR1 (AA: 28-156)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using IFNAR1 mAb against HEK293-6e (1) and IFNAR1 (AA: 28-156)-hIgGFc transfected HEK293-6e (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using IFNAR1 mouse mAb against mouse lung (1) lysate.
Figure 4:Western blot analysis using IFNAR1 mouse mAb against mouse lung (1) lysate.
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of K562 cells using IFNAR1 mouse mAb (green) and negative control (red).
Figure 5:Flow cytometric analysis of K562 cells using IFNAR1 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using IFNAR1 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using IFNAR1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using IFNAR1 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using IFNAR1 mouse mAb with DAB staining.
Product Overview
Description

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

References (references)
References (references)1.J Clin Invest. 2021 Jan 4;131(1):e139980.
2.Front Immunol. 2021 Mar 5;12:628364.