HIST2H3C(27Ac) Primary Antibody
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Flow cytometric analysis of *** cells using *** mouse mAb (green) and negative control (red).
Figure 3:Flow cytometric analysis of *** cells using HIST2H3C(27Ac) mouse mAb (green) and negative control (red).
Figure 4:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using HIST2H3C(27Ac) mouse mAb with DAB staining.
Figure 5:Immunohistochemical analysis of paraffin-embedded breast cancer tissues using HIST2H3C(27Ac) mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.