HDAC4 Primary Antibody
Item Information
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Price
Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Product Overview
Entrez GenelD
9759
Aliases
HD4; HDACA; HA6116; HDAC-A; KIAA0288; HDAC4
Clone#
7B2
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human HDAC4 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Biochem Biophys Res Commun. 2008 Dec 19;377(3):852-6.
2. Curr Top Med Chem. 2009;9(3):235-40.
3. Nucleic Acids Res. 2010 May;38(9):2813-24.
2. Curr Top Med Chem. 2009;9(3):235-40.
3. Nucleic Acids Res. 2010 May;38(9):2813-24.
Product Image
Western Blot
Figure 1: Western blot analysis using HDAC4 mouse mAb against Hela (1), Jurkat (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.