GLUL Primary Antibody
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
![Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-elisa_31951ea_12.jpg?v=1666705008)
![Figure 2: Western blot analysis using GLUL mAb against human GLUL (AA: 2-121) recombinant protein. (Expected MW is 30.7 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-wb_31951rwb_13.jpg?v=1666705008)
![Figure 3: Western blot analysis using GLUL mAb against HEK293-6e (1) and GLUL (AA: 2-121)-hIgGFc transfected HEK293-6e (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-wb_31951twb_14.jpg?v=1666705008)
![Figure 4: Western blot analysis using GLUL mouse mAb against Jurkat (1), and mouse liver (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-wb_31951lwb_15.jpg?v=1666705008)
![Figure 5: Flow cytometric analysis of Hela cells using GLUL mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-fcm_31951fcm_16.jpg?v=1666705008)
![Figure 6: Immunohistochemical analysis of paraffin-embedded cerebellar tissues using GLUL mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-icc_31951ihc_17.jpg?v=1666705008)
![Figure 7: Immunofluorescence analysis of hela cells using GLUL mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-icc_31951icc_18.jpg?v=1666705008)