GFAP Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesFLJ45472; GFAP
ProductOrderG
Clone#6A6
Entrez GenelD2670
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human GFAP expressed in E. Coli.
MW50kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
292-432
Catalog#: 30108
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using GFAP mouse mAb against A431 (1), SK-N-SH (2) and PC12 (3) cell lysate.
Figure 1: Western blot analysis using GFAP mouse mAb against A431 (1), SK-N-SH (2) and PC12 (3) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded brain tissues using GFAP mouse mAb with DAB staining
Figure 2: Immunohistochemical analysis of paraffin-embedded brain tissues using GFAP mouse mAb with DAB staining
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of paraffin-embedded lobe of brain tissues using GFAP mouse mAb (green).
Figure 3: Immunofluorescence analysis of paraffin-embedded lobe of brain tissues using GFAP mouse mAb (green).
Product Overview
Description

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.Tissue specificity: Expressed in cells lacking fibronectin.ABCAM:It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves.In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.

References (references)
References (references)1. Acta Neuropathol. 2009 Jun;117(6):667-75.
2. Schizophr Res. 2009 Jul;112(1-3):54-64.