G6PD Primary Antibody
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human G6PD expressed in E. Coli. |
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using G6PD mAb against human G6PD (AA: 275-515) recombinant protein.(Expected MW is 53.1 kDa)
Figure 2: Western blot analysis using G6PD mouse mAb against Hela (1), MCF-7 (2), Jurkat (3) and K562 (4) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using G6PD mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using G6PD mouse mAb with DAB staining.
Figure 5: Flow cytometric analysis of MCF-7 cells using G6PD mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
|References (references)||1. Science. 2009 Dec 11;326(5959):1546-9. |
2. Immunol Invest. 2009;38(6):551-9.