FOXP2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSPCH1; CAGH44; TNRC10; DKFZp686H1726
ProductOrderF
Clone#5C11A8
Entrez GenelD93986
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MAPK3 expressed in E. Coli.
MW85kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
47-287
Catalog#: 30268
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Images
Western Blot
Figure 1: Western blot analysis using FOXP2 mAb against human FOXP2 (AA: 47-287) recombinant protein. (Expected MW is 52.8 kDa)
Figure 1: Western blot analysis using FOXP2 mAb against human FOXP2 (AA: 47-287) recombinant protein. (Expected MW is 52.8 kDa)
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

References (references)
References (references)1. Nature. 2009 Nov 12;462(7270):213-7.
2. Mol Biol Evol. 2009 Oct;26(10):2181-4.