ERK3 Primary Antibody
|Aliases||ERK3; PRKM6; p97MAPK; HsT17250; DKFZp686F03189; MAPK6|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human ERK3 expressed in E. Coli. |
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using ERK3 mAb against HEK293 (1) and ERK3(AA: 347-582)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Flow cytometric analysis of Hela cells using ERK3 mouse mAb (green) and negative control (purple).
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts
|References (references)||1. J Cell Physiol. 2008 Dec;217(3):778-88. |
2. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5.