ERK3 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesERK3; PRKM6; p97MAPK; HsT17250; DKFZp686F03189; MAPK6
ProductOrderE
Clone#4E8
Entrez GenelD5597
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ERK3 expressed in E. Coli.
MW105kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
347-582
Catalog#: 30194
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Images
Western Blot
Figure 1: Western blot analysis using ERK3 mAb against HEK293 (1) and ERK3(AA: 347-582)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 1: Western blot analysis using ERK3 mAb against HEK293 (1) and ERK3(AA: 347-582)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of Hela cells using ERK3 mouse mAb (green) and negative control (purple).
Figure 2: Flow cytometric analysis of Hela cells using ERK3 mouse mAb (green) and negative control (purple).
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts

References (references)
References (references)1. J Cell Physiol. 2008 Dec;217(3):778-88.
2. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5.