ERK3 Primary Antibody
Item Information
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Size
Price
Description
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts
Product Overview
Entrez GenelD
5597
Aliases
ERK3; PRKM6; p97MAPK; HsT17250; DKFZp686F03189; MAPK6
Clone#
4E8
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ERK3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. J Cell Physiol. 2008 Dec;217(3):778-88.
2. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5.
2. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5.
Product Image
Western Blot
Figure 1: Western blot analysis using ERK3 mAb against HEK293 (1) and ERK3(AA: 347-582)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of Hela cells using ERK3 mouse mAb (green) and negative control (purple).
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
For Research Use Only. Not for use in diagnostic procedures.