EphB3 Primary Antibody

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EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using EphB3 mouse mAb against truncated EphB3-His recombinant protein.
Figure 1: Western blot analysis using EphB3 mouse mAb against truncated EphB3-His recombinant protein.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung squamous cell carcinoma (A), lung adenocarcinoma (B), colon carcinoma (C), breast carcinoma (D), normal sublingual gland (E), normal rectal (F), showing membrane localization with DAB staining using EphB3 mouse mAb.
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung squamous cell carcinoma (A), lung adenocarcinoma (B), colon carcinoma (C), breast carcinoma (D), normal sublingual gland (E), normal rectal (F), showing membrane localization with DAB staining using EphB3 mouse mAb.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded human Adrenal tissues using EPHB3 mouse mAb
Figure 3: Immunohistochemical analysis of paraffin-embedded human Adrenal tissues using EPHB3 mouse mAb
For Research Use Only. Not for use in diagnostic procedures.