EphA8 Primary Antibody
EphA8: EPH receptor A8. This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
2. Oncogene. 2005 Jun 16;24(26):4243-56.
![Figure 1: Western blot analysis using EphA8 mouse mAb against truncated Trx-EphA8 recombinant protein (1) and truncated MBP-EphA8(aa70-150) recombinant protein (2).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/20266rwb.jpg?v=1666698670)