EhpB1 Primary Antibody
EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.
Ascitic fluid containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using EhpB1 mouse mAb against MDA-MB-468 (1), MDA-MB-453 (2), MCF-7 (3), T47D (4) and SKBR-3 (5) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and colon cancer (right) showing cytoplasmic localization with DAB staining using EphB1 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.