DLG4

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMRD62; PSD95; SAP90; SAP-90
Clone#2D5H2
Entrez GenelD1742
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human DLG4 (AA: 54-300) expressed in HEK293-6e cells supernatant.
MW80.4kDa
Species ReactivityHuman, Mouse, Rat
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
54-300
Catalog#: 32289
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using DLG4 mAb against human DLG4 (AA: 54-300) recombinant protein. (Expected MW is 57 kDa)
Figure 2:Western blot analysis using DLG4 mAb against human DLG4 (AA: 54-300) recombinant protein. (Expected MW is 57 kDa)
Western Blot
Figure 4:Western blot analysis using DLG4 mouse mAb against Mouse brain (1), and Rat brain (2) tissue lysate.
Figure 4:Western blot analysis using DLG4 mouse mAb against Mouse brain (1), and Rat brain (2) tissue lysate.
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of LNCAP cells using DLG4 mouse mAb (green) and negative control (red).
Figure 5:Flow cytometric analysis of LNCAP cells using DLG4 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded human brain tissues using DLG4 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded human brain tissues using DLG4 mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

References (references)
References (references)1.J Mol Neurosci. 2020 Sep;70(9):1389-1402.
2.J Biol Chem. 2020 Feb 14;295(7):1992-2000.
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