DCN Primary Antibody
|Aliases||CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human DCN (AA: 263-324) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using DCN mAb against human DCN recombinant protein. (Expected MW is 32.5 kDa)
Figure 2: Western blot analysis using DCN mAb against HEK293 (1) and DCN (AA: 263-324)-hIgGFc transfected HEK293 (2) cell lysate.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. |
|References (references)||1. PLoS One. 2012;7(9):e45559. |
2. Hum Reprod. 2012 Nov;27(11):3249-58.