Cytokeratin 19 Primary Antibody

Item Information
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Price
Description

Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Product Overview
Entrez GenelD
3880
Aliases
CK19; K1CS; MGC15366; KRT19
Clone#
9H8G6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of Cytokeratin 19 (aa80-400) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Lung Cancer. 2007 Dec;58(3):369-75.
2. Endocr Pract. 2008 Mar;14(2):168-74.
Product Image
Western Blot
Figure 1: Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein (1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Figure 1: Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein (1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using KRT19 mouse mAb.
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using KRT19 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.