Cytokeratin 19 Primary Antibody
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Description
Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using anti-KRT19 monoclonal antibody against truncated KRT19-His recombinant protein (1) and full-length KRT19(aa1-400)-hIgGFc transfected CHO-K1 cell lysate(2).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using KRT19 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.