CXCR7

Item Information

Catalog #

Size

Price

Description

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Product Overview

Entrez GenelD

57007

Aliases

RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159

Clone#

5E6C8

Host / Isotype

Mouse / Mouse IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human CXCR7(AA: extra mix) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4℃; -20℃ for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ICC (Immunocytochemistry)

1/50 - 1/200

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1,Ann Diagn Pathol. 2020 Dec;49:151621.
2,Respir Res. 2020 Oct 31;21(1):287.

Product Image

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using CXCR7 mAb against human CXCR7 (AA: extra mix) recombinant protein. (Expected MW is 28.4 kDa)

Western Blot

Figure 3:Western blot analysis using CXCR7 mAb against HEK293-6e (1) and CXCR7 (AA: extra mix)-hIgGFc transfected HEK293-6e (2) cell lysate.

Immunohistochemical analysis

Figure 4:Immunofluorescence analysis of Hela cells using CXCR7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis