This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
Purified antibody in PBS with 0.05% sodium azide
4℃; -20℃ for long term storage
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CXCR7 mAb against human CXCR7 (AA: extra mix) recombinant protein. (Expected MW is 28.4 kDa)
Figure 3:Western blot analysis using CXCR7 mAb against HEK293-6e (1) and CXCR7 (AA: extra mix)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 4:Immunofluorescence analysis of Hela cells using CXCR7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 5:Flow cytometric analysis of MCF-7 cells using CXCR7 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CXCR7 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CXCR7 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.