CTNNBL1 Primary Antibody

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Description

The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.

Product Overview

Formulation

Purified antibody in PBS with 0.05% sodium azide.

Storage

4°C; -20°C for long term storage

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Western Blot

Figure 1: Western blot analysis using CTNNBL1 mAb against human CTNNBL1 (AA: 390-557) recombinant protein. (Expected MW is 45.8 kDa)

Western Blot

Figure 2: Western blot analysis using CTNNBL1 mAb against HEK293 (1) and CTNNBL1 (AA: 390-557)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot

Figure 3: Western blot analysis using CTNNBL1 mouse mAb against Hela (1), Jurkat (2), HEK293 (3), A431 (4), HepG2 (5), RAJI (6) cell lysate.

Immunofluorescence analysis

Figure 4: Immunofluorescence analysis of MCF-7 cells using CTNNBL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric