COX4I1 Primary Antibody
Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.
2. Histochemistry. 1990;94(2):211-5.
3. FEBS Lett. 2000 Jun 30;476(1-2):22-6.
![Figure 1: Western blot analysis using COX4I1 mouse mAb against HEK293 (1), A549 (2) and PC12 (3) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30096lwb.jpg?v=1666699088)
![Figure 2: Immunofluorescence analysis of PANC-1 cells using COX4I1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30096icc.jpg?v=1666699088)
![Figure 3: Flow cytometric analysis of K562 cells using COX4I1 mouse mAb (blue) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30096fcm.jpg?v=1666699088)