COX4I1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCOX4; COXIV; COX4-1; MGC72016; COX4I1
ProductOrderC
Clone#6B3
Entrez GenelD1327
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human COX4I1 expressed in E. Coli.
MW19kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Monkey, Rat, Mouse
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
full(1-169)
Catalog#: 30096
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Images
Western Blot
Figure 1: Western blot analysis using COX4I1 mouse mAb against HEK293 (1), A549 (2) and PC12 (3) cell lysate.
Figure 1: Western blot analysis using COX4I1 mouse mAb against HEK293 (1), A549 (2) and PC12 (3) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of PANC-1 cells using COX4I1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of PANC-1 cells using COX4I1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Flow cytometric
Figure 3: Flow cytometric analysis of K562 cells using COX4I1 mouse mAb (blue) and negative control (red).
Figure 3: Flow cytometric analysis of K562 cells using COX4I1 mouse mAb (blue) and negative control (red).
Product Overview
Description

Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.

References (references)
References (references)1. Biochim Biophys Acta. 1992 Feb 26;1119(2):218-24.
2. Histochemistry. 1990;94(2):211-5.
3. FEBS Lett. 2000 Jun 30;476(1-2):22-6.