CK7 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesKRT7; cytokeratin 7
ProductOrderC
Clone#5D12
Entrez GenelD3855
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CK7 expressed in E. Coli.
MW51kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
88-222
Catalog#: 30013
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Images
Western Blot
Figure 1: Western blot analysis using CK7 mouse mAb against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate.
Figure 1: Western blot analysis using CK7 mouse mAb against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of Hela cells using anti-CK7 mAb (green) and negative control (purple).
Figure 2: Flow cytometric analysis of Hela cells using anti-CK7 mAb (green) and negative control (purple).
Product Overview
Description

CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

References (references)
References (references)1. Cytogenet Cell Genet. 1991;57(1):33-8.
2. J Pathol. 1998 Mar;184(3):234-9.
3. J Cell Biol. 2006 Jul 17;174(2):169-74.