CK5 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesKRT5; K5; DDD; EBS2; KRT5A
ProductOrderC
Clone#10C11E6
Entrez GenelD3852
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CK5 (AA: 316-590) expressed in E. Coli.
MW62.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
316-590
Catalog#: 30542
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Images
Western Blot
Figure 1: Western blot analysis using CK5 mAb against human CK5 recombinant protein. (Expected MW is 47.8 kDa)
Figure 1: Western blot analysis using CK5 mAb against human CK5 recombinant protein. (Expected MW is 47.8 kDa)
Western Blot
Figure 2: Western blot analysis using CK5 mouse mAb against A431 cell lysate.
Figure 2: Western blot analysis using CK5 mouse mAb against A431 cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CK5 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CK5 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using CK5 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using CK5 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
References (references)
References (references)1. Mol Biol Cell. 2011 Nov;22(21):4068-78.
2. Am J Surg Pathol. 2009 Nov;33(11):1615-23.