CFLAR Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
ProductOrderC
Clone#7A3D12
Entrez GenelD8837
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
MW55kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
100-251
Catalog#: 30511
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Images
Western Blot
Figure 1: Western blot analysis using CFLAR mAb against human CFLAR recombinant protein. (Expected MW is 42.9 kDa)
Figure 1: Western blot analysis using CFLAR mAb against human CFLAR recombinant protein. (Expected MW is 42.9 kDa)
Western Blot
Figure 2: Western blot analysis using CFLAR mouse mAb against JURKAT (1), 3T3L1 (2) and RAJI (3) cell lysate.
Figure 2: Western blot analysis using CFLAR mouse mAb against JURKAT (1), 3T3L1 (2) and RAJI (3) cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of JURKAT cells using CFLAR mouse mAb (green) and negative control (red).
Figure 3: Flow cytometric analysis of JURKAT cells using CFLAR mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CFLAR mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CFLAR mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using CFLAR mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using CFLAR mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThe protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.


References (references)
References (references)1. PLoS One. 2012;7(9):e44917.
2. Cancer Prev Res (Phila). 2012 Apr;5(4):612-20.