CEBPB Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesLAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080; C/EBP-beta
ProductOrderC
Clone#3H9
Entrez GenelD1051
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CEBPB expressed in E. Coli.
MW36kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
161-338
Catalog#: 30258
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Images
Western Blot
Figure 1: Western blot analysis using CEBPB mAb against human CEBPB (AA: 161-338) recombinant protein. (Expected MW is 44.5 kDa)
Figure 1: Western blot analysis using CEBPB mAb against human CEBPB (AA: 161-338) recombinant protein. (Expected MW is 44.5 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of MCF-7 cells using CEBPB mouse mAb (blue) and negative control (red).
Figure 2: Flow cytometric analysis of MCF-7 cells using CEBPB mouse mAb (blue) and negative control (red).
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

References (references)
References (references)1. Biochem J. 2009 Dec 14;425(1):215-23.
2. Cell Signal. 2009 Dec;21(12):1918-24.