CEBPA Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCEBP; C/EBP-alpha
ProductOrderC
Clone#4E10
Entrez GenelD1050
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CEBPA expressed in E. Coli.
MW37.5kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
139-204
Catalog#: 30347
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Images
Western Blot
Figure 1: Western blot analysis using CEBPA mAb against human CEBPA (AA: 139-204) recombinant protein. (Expected MW is 32.7 kDa)
Figure 1: Western blot analysis using CEBPA mAb against human CEBPA (AA: 139-204) recombinant protein. (Expected MW is 32.7 kDa)
Western Blot
Figure 2: Western blot analysis using CEBPA mouse mAb against THP-1 (1)cell lysate.
Figure 2: Western blot analysis using CEBPA mouse mAb against THP-1 (1)cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of HeLa cells using CEBPA mouse mAb (green) and negative control (red).
Figure 3: Flow cytometric analysis of HeLa cells using CEBPA mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

References (references)
References (references)Haematologica. 2009 Aug;94(8):1075-84.
Br J Cancer. 2009 Aug 18;101(4):738-40.