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CEA Primary Antibody
|Aliases||CEA; CD66e; DKFZp781M2392; CEACAM5|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human CEA expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|ICC (Immunocytochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1: Western blot analysis using CEA mAb against HEK293 (1) and CEA(AA: 460-600)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Immunofluorescence analysis of PANC-1 cells using CEA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
|Description||Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and a useful tumor marker for adenocarcinoma. Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.|
|References (references)||1. Scand J Clin Lab Invest. 2008;68(8):703-13.
2. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Apr;24(4):370-2. Chinese.