CDK9 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTAK; C-2k; CTK1; CDC2L4; PITALRE
ProductOrderC
Clone#1B5A7
Entrez GenelD1025
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CDK9 expressed in E. Coli.
MW43kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
178-369
Catalog#: 30211
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Images
Western Blot
Figure 1: Western blot analysis using CDK9 mAb against HEK293 (1) and CDK9(AA: 178-369)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 1: Western blot analysis using CDK9 mAb against HEK293 (1) and CDK9(AA: 178-369)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues (left) and placenta tissues (right) using CDK9 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues (left) and placenta tissues (right) using CDK9 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded brain tissues (left) and esophageal cancer tissues (right) using CDK9 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded brain tissues (left) and esophageal cancer tissues (right) using CDK9 mouse mAb with DAB staining.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

References (references)
References (references)1. J Biol Chem. 2008 Mar 21;283(12):7368-78.
2. Mol Cell Biol. 2008 Apr;28(7):2201-12.