CD74 Primary Antibody
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Description
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Western Blot
Figure 1: Western blot analysis using CD74 mAb against human CD74 recombinant protein. (Expected MW is 37.6 kDa)
Western Blot
Figure 2: Western blot analysis using CD74 mAb against HEK293 (1) and CD74 (AA: 1-106)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of Hela cells using CD74 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Western Blot
Figure 3: Western blot analysis using CD74 mouse mAb against Raji cell lysate.
Flow cytometric
Figure 4: Flow cytometric analysis of Jurkat cells using CD74 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.