CD74 Primary Antibody
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Western blot analysis using CD74 mAb against human CD74 recombinant protein. (Expected MW is 37.6 kDa)
Figure 2: Western blot analysis using CD74 mAb against HEK293 (1) and CD74 (AA: 1-106)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using CD74 mouse mAb against Raji cell lysate.
Figure 4: Flow cytometric analysis of Jurkat cells using CD74 mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.