CD63 Primary Antibody
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CD63 mAb against human CD63 (AA: extra 103-203) recombinant protein. (Expected MW is 37.4 kDa)
Figure 3:Western blot analysis using CD63 mAb against HEK293 (1) and CD63 (AA: extra 103-203)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of HL-60 cells using CD63 mouse mAb (green) and negative control (red).
Figure 5:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD63 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.