CD44 Primary Antibody
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 4:Western blot analysis using CD44 mouse mAb against Hela (1), PANC-1 (2), HUVEC (3), and HUVE-12 (4) cell lysate.
Figure 5:Flow cytometric analysis of Hela cells using CD44 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CD44 mouse mAb with DAB staining.
Figure 6:Western blot analysis using CD44 mAb against human CD44 (AA: extra 36-194) recombinant protein. (Expected MW is 43.3 kDa)
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD44 mouse mAb with DAB staining.
Figure 7:Western blot analysis using CD44 mAb against HEK293 (1) and CD44 (AA: extra 36-194)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.