CD42A Primary Antibody

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Description

This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.

Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD42A mAb against human CD42A (AA: extra 17-147) recombinant protein. (Expected MW is 40.3 kDa)
Figure 2:Western blot analysis using CD42A mAb against human CD42A (AA: extra 17-147) recombinant protein. (Expected MW is 40.3 kDa)
Western Blot
Figure 3:Western blot analysis using CD42A mAb against HEK293 (1) and CD42A (AA: extra 17-147)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using CD42A mAb against HEK293 (1) and CD42A (AA: extra 17-147)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD42A mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of HL-60 cells using CD42A mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.