CD334 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
Product Overview
Entrez GenelD
2264
Aliases
FGFR4; TKF; JTK2
Clone#
3B5B8
Host / Isotype
Mouse / Mouse IgG1
Immunogen
Purified recombinant fragment of human CD334 (AA: extra 22-369) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4?; -20? for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Carcinog. 2018 Aug;57(8):988-996. 2.Oncotarget. 2016 Oct 25;7(43):69976-69990.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD334 mAb against human CD334 (AA: extra 22-369) recombinant protein. (Expected MW is 64.5 kDa)
Western Blot
Figure 3:Western blot analysis using CD334 mAb against HEK293 (1) and CD334 (AA: extra 22-369)-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD334 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.