CD307C Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Product Overview
Entrez GenelD
115352
Aliases
FCRL3; FCRH3; IFGP3; IRTA3; SPAP2
Clone#
4B4B2
Host / Isotype
Mouse / IgG2a
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD307C (AA: extra 18-153) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Hum Immunol. 2016 Feb;77(2):223-9.
2.Autoimmunity. 2013 Dec;46(8):547-58.
2.Autoimmunity. 2013 Dec;46(8):547-58.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD307C mAb against human CD307C (AA: extra 18-153) recombinant protein. (Expected MW is 45.2 kDa)
Western Blot
Figure 3:Western blot analysis using CD307C mAb against HEK293 (1) and CD307C (AA: extra 18-153)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD307C mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.