CD218A Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Product Overview
Entrez GenelD
8809
Aliases
IL18R1; IL18RA; IL1RRP; CDw218a; IL-1Rrp
Clone#
2B7E6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD218A (AA: extra 22-185) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.PLoS One. 2014 Oct 31;9(10):e110734.
2.Mult Scler. 2010 Sep;16(9):1056-65.
2.Mult Scler. 2010 Sep;16(9):1056-65.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD218A mAb against human CD218A (AA: extra 22-185) recombinant protein. (Expected MW is 45.2 kDa)
Western Blot
Figure 3:Western blot analysis using CD218A mAb against HEK293 (1) and CD218A (AA: extra 22-185)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD218A mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.