CD218A Primary Antibody

Item Information
Catalog # Size/Concentration Price
31684 100μg $341.00
Specification
AliasesIL18R1; IL18RA; IL1RRP; CDw218a; IL-1Rrp
Clone#2B7E6
Entrez GeneID8809
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CD218A (AA: extra 22-185) expressed in E. Coli.
MW62.3kDa
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
Extra (22-185)
Catalog
31684
$341.00
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Images

Elisa

Cell Culture Products

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products

Figure 2:Western blot analysis using CD218A mAb against human CD218A (AA: extra 22-185) recombinant protein. (Expected MW is 45.2 kDa)

Western Blot

Cell Culture Products

Figure 3:Western blot analysis using CD218A mAb against HEK293 (1) and CD218A (AA: extra 22-185)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric

Cell Culture Products

Figure 4:Flow cytometric analysis of HL-60 cells using CD218A mouse mAb (green) and negative control (red).

Product Overview
Description

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

References (references)
References (references) 1.PLoS One. 2014 Oct 31;9(10):e110734.
2.Mult Scler. 2010 Sep;16(9):1056-65.

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