CD183 Primary Antibody
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CD183 mAb against human CD183 (AA: extra mix) recombinant protein. (Expected MW is 38.3 kDa)
Figure 3:Western blot analysis using CD183 mAb against HEK293 (1) and CD183 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using CD183 mouse mAb against Hela (1) and L-02 (2) cell lysate.
Figure 5:Flow cytometric analysis of Jurkat cells using CD183 mouse mAb (green) and negative control (red).
Figure 6:Flow cytometric analysis of Ramos cells using CD183 mouse mAb (green) and negative control (red).
Figure 7:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD183 mouse mAb with DAB staining.
Figure 8:Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CD183 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.