CD152 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Product Overview
Entrez GenelD
1493
Aliases
CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3
Clone#
8B3F8
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Asian Pac J Cancer Prev. 2016;17(8):3785-91.
2.Eur J Cancer. 2015 Nov;51(17):2689-97.
2.Eur J Cancer. 2015 Nov;51(17):2689-97.
Product Image
Elisa
Figure 1: Figure 4:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD152 mAb against human CD152 (AA: extra 36-161) recombinant protein. (Expected MW is 39.5 kDa)
Western Blot
Figure 3:Western blot analysis using CD152 mAb against HEK293 (1) and CD152 (AA: extra 36-161)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Ramos cells using CD152 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.