CD129 Primary Antibody
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CD129 mAb against human CD129 (AA: extra 41-270) recombinant protein. (Expected MW is 51.9 kDa)
Figure 3:Western blot analysis using CD129 mAb against HEK293 (1) and CD129 (AA: extra 41-270)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using CD129 mouse mAb against C6 (1) and PC-3 (2) cell lysate.
Figure 5:Flow cytometric analysis of Ramos cells using CD129 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD129 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using CD129 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.