CASP6 Primary Antibody

Item Information
Catalog #
Size
Price
Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Product Overview
Entrez GenelD
839
Aliases
MCH2
Clone#
3B7C3
Host / Isotype
Mouse / IgG2a
Immunogen
Purified recombinant fragment of human CASP6 (AA: 194–293) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Biochemistry. 2017 Aug 29;56(34):4568-4577.
2.Acta Neuropathol Commun. 2016 Dec 8;4(1):127.
For Research Use Only. Not for use in diagnostic procedures.