CASP-7 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMCH3; CMH-1; LICE2; CASP7; ICE-LAP3
ProductOrderC
Clone#4D10B2
Entrez GenelD840
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.
MW34.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
29-198
Catalog#: 30727
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Images
Western Blot
Figure 1: Western blot analysis using CASP-7 mAb against human CASP-7 (AA: 29-198) recombinant protein. (Expected MW is 22.5 kDa)
Figure 1: Western blot analysis using CASP-7 mAb against human CASP-7 (AA: 29-198) recombinant protein. (Expected MW is 22.5 kDa)
Western Blot
Figure 2: Western blot analysis using CASP-7 mAb against HEK293 (1) and CASP-7 (AA: 29-198)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using CASP-7 mAb against HEK293 (1) and CASP-7 (AA: 29-198)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 3: Western blot analysis using CASP-7 mouse mAb against Jurkat (1), HEK293 (2), MOLT4 (3), MCF-7 (4), PC-12 (5) cell lysate.
Figure 3: Western blot analysis using CASP-7 mouse mAb against Jurkat (1), HEK293 (2), MOLT4 (3), MCF-7 (4), PC-12 (5) cell lysate.
Flow cytometric
Figure 4: Flow cytometric analysis of MCF-7 cells using CASP-7 mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of MCF-7 cells using CASP-7 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CASP-7 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CASP-7 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References (references)
References (references)1. Lung Cancer. 2009 Jul;65(1):19-24.
2. Genes Cells. 2008 Jun;13(6):609-21.