CA9 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMN; CAIX; CA9
ProductOrderC
Clone#2D3
Entrez GenelD768
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CA9 expressed in E. Coli.
MW50kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
37-291
Catalog#: 30148
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Images
Western Blot
Figure 1: Western blot analysis using CA9 mouse mAb against Hela (1) and A549 (2) cell lysate.
Figure 1: Western blot analysis using CA9 mouse mAb against Hela (1) and A549 (2) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded stomach tissues (left) and colon tissues (right) using CA9 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded stomach tissues (left) and colon tissues (right) using CA9 mouse mAb with DAB staining.
Flow cytometric
Figure 3: Flow cytometric analysis of NTERA-2 cells using CA9 mouse mAb (green) and negative control (purple).
Figure 3: Flow cytometric analysis of NTERA-2 cells using CA9 mouse mAb (green) and negative control (purple).
Product Overview
Description

CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. Tissue specificity: Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

References (references)
References (references)1. Br J Cancer. 2008 Sep 2;99(5):727-33.
2. Pathol Res Pract. 2009;205(1):1-9.