c-Rel Primary Antibody

Item Information

Catalog #

Size

Price

Description

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.

Product Overview

Entrez GenelD

5966

Aliases

Rel; c-Rel

Clone#

1E7

Host / Isotype

Mouse / IgG1

Species Reactivity

Human, Mouse

Immunogen

Purified recombinant fragment of human c-Rel expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ICC (Immunocytochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. Gut. 2009 Aug;58(8):1078-83.
2. Gene Expr. 2008;14(4):195-205.

Product Image

Western Blot

Figure 1: Western blot analysis using c-Rel mouse mAb against Jurkat (1), NIH/3T3 (2), Hela (3), HEK293 (4) and RAJI (5) cell lysate.

Immunohistochemical analysis

Figure 2: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues (left) and liver cancer tissues (right) using c-Rel mouse mAb with DAB staining.

Immunofluorescence analysis

Figure 3: Immunofluorescence analysis of U251 cells using c-Rel mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

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