BAK1 Primary Antibody
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using BAK1 mAb against human BAK1 (AA: 29-187) recombinant protein. (Expected MW is 43.9 kDa)
Figure 3:Western blot analysis using BAK1 mAb against HEK293 (1) and BAK1 (AA: 29-187)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of Hela cells using BAK1 mouse mAb (green) and negative control (red).
Figure 5:Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using BAK1 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using BAK1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.