ATG4B Primary Antibody
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31752ea_35.jpg?v=1666704459)
![Figure 2:Western blot analysis using ATG4B mAb against human ATG4B (AA: 1-221) recombinant protein. (Expected MW is 51 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31752rwb_36.jpg?v=1666704459)
![Figure 3:Western blot analysis using ATG4B mAb against HEK293 (1) and ATG4B (AA: 1-221)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31752twb_37.jpg?v=1666704459)
![Figure 4:Western blot analysis using ATG4B mouse mAb against Hela (1), Ramos (2), and Jurkat (3) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31752lwb_38.jpg?v=1666704459)
![Figure 5:Flow cytometric analysis of Hela cells using ATG4B mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31752fcm_39.jpg?v=1666704459)