ARG1 Primary Antibody

Item Information
Catalog #	Size/Concentration	Price
32008	100ug	$341.00

Specification
Aliases	ARG1
Clone#	7D1D10
Entrez GeneID	383
Formulation	Purified antibody in PBS with 0.05% sodium azide
Host	Mouse
Isotype	Mouse IgG1
Immunogen	Purified recombinant fragment of human ARG1 (AA: (1-322)) expressed in E. Coli.
MW	34.7kDa

Sequence
AA: 1-322

Images

Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

Figure 2: Western blot analysis using ARG1 mAb against human ARG1 (AA: (1-322)) recombinant protein. (Expected MW is 38.6 kDa)

Figure 3: Western blot analysis using ARG1 mAb against HEK293-6e (1) and ARG1 (AA: (1-322))-hIgGFc transfected HEK293-6e (2) cell lysate.

Figure 4: Flow cytometric analysis of BEL-7402 cells using ARG1 mouse mAb (green) and negative control (red).

Figure 5: Flow cytometric analysis of Hepg2 cells using ARG1 mouse mAb (green) and negative control (red).

Figure 6: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ARG1 mouse mAb with DAB staining.

Figure 7: Immunohistochemical analysis of paraffin-embedded Stomach cancer tissues using ARG1 mouse mAb with DAB staining.

Product Overview

Description	Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

References (references)

References (references)	1,Medicine (Baltimore). 2020 Aug 7;99(32):e21634.2,Medicine (Baltimore). 2019 Nov;98(47):e17694.