ANXA1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesANX1; LPC1
ProductOrderA
Clone#2F1
Entrez GenelD301
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ANXA1 (AA: 144-248 ) expressed in E. Coli.
MW38.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse, Monkey
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
144-248
Catalog#: 30406
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Images
Western Blot
Figure 1: Western blot analysis using ANXA1 mAb against human ANXA1 recombinant protein. (Expected MW is 33.7 kDa)
Figure 1: Western blot analysis using ANXA1 mAb against human ANXA1 recombinant protein. (Expected MW is 33.7 kDa)
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using ANXA1 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using ANXA1 mouse mAb with DAB staining.
Western Blot
Figure 2: Western blot analysis using ANXA1 mouse mAb against Hela (1), A549 (2), K562 (3), NIH3T3 (4), C6 (5), and COS7 (6) cell lysate.
Figure 2: Western blot analysis using ANXA1 mouse mAb against Hela (1), A549 (2), K562 (3), NIH3T3 (4), C6 (5), and COS7 (6) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ANXA1 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ANXA1 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

References (references)
References (references)1.Cancer Lett. 2010 Aug 1;294(1):111-7. 2.Pathology. 2010 Jan;42(1):43-9.