ANXA1 Primary Antibody
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human ANXA1 (AA: 144-248 ) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|Species Reactivity||Human, Mouse, Monkey|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using ANXA1 mAb against human ANXA1 recombinant protein. (Expected MW is 33.7 kDa)
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using ANXA1 mouse mAb with DAB staining.
Figure 2: Western blot analysis using ANXA1 mouse mAb against Hela (1), A549 (2), K562 (3), NIH3T3 (4), C6 (5), and COS7 (6) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ANXA1 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
|References (references)||1.Cancer Lett. 2010 Aug 1;294(1):111-7. 2.Pathology. 2010 Jan;42(1):43-9.|