ALPP Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesALP; PALP; PLAP; FLJ61142; ALPP
ProductOrderA
Clone#3E5
Entrez GenelD250
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG2b
ImmunogenPurified recombinant fragment of human ALPP expressed in E. Coli.
MW58kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
23-506
Catalog#: 30061
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate.
Figure 1: Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining.
Product Overview
Description

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

References (references)
References (references)1. J Cell Biochem. 2003 Apr 1;88(5):1025-37.
2. J Mol Biol. 2005 Jul 15;350(3):441-51.