ALPP Primary Antibody

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Description

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Product Overview
Entrez GenelD
250
Aliases
ALP; PALP; PLAP; FLJ61142; ALPP
Clone#
3E5
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ALPP expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. J Cell Biochem. 2003 Apr 1;88(5):1025-37.
2. J Mol Biol. 2005 Jul 15;350(3):441-51.
Product Image
Western Blot
Figure 1: Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate.
Figure 1: Western blot analysis using ALPP mouse mAb against HepG2 (1), A431 (2) and MCF-7 (3) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (A), stomach cancer (B) using ALPP mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.