The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
Purified antibody in PBS with 0.05% sodium azide
4℃; -20℃ for long term storage
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using ALDH1L1 mAb against human ALDH1L1 (AA: 10-222) recombinant protein. (Expected MW is 26.5 kDa)
Figure 3:Western blot analysis using ALDH1L1 mAb against HEK293-6e (1) and ALDH1L1 (AA: 10-222)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 4:Western blot analysis using ALDH1L1 mouse mAb against Rat kidney (1), Mouse liver (2), Rat liver (3) and Mouse kidney (4) tissue lysate.
Figure 5:Flow cytometric analysis of Jurkat cells using ALDH1L1 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ALDH1L1 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using ALDH1L1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.