Akt3 Primary Antibody

Item Information
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Price
Description

Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.

Product Overview
Entrez GenelD
10000
Aliases
Akt3
Clone#
3B12F3F10; 2D2B11B11; 2D2B11H5
Species Reactivity
Human
Immunogen
Purified recombinant fragment of Akt3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Rachael M. Easton, Han Cho, Kristin Roovers. Mol. Cell. Biol., Mar 2005; 25: 1869 - 1878
2. Jill M. Stahl, Arati Sharma, Mitchell Cheung. Cancer Res., Oct 2004; 64: 7002-7010
Product Image
Western Blot
Figure 1: Western blot analysis using Akt3 mouse mAb against truncated Akt3 recombinant protein (1) and human ovary carcinoma tissue lysate (2).
Figure 1: Western blot analysis using Akt3 mouse mAb against truncated Akt3 recombinant protein (1) and human ovary carcinoma tissue lysate (2).
For Research Use Only. Not for use in diagnostic procedures.