ABCC4 Primary Antibody
|Aliases||MRP4; MOATB; MOAT-B; EST170205|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human ABCC4 (AA: 631-692) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using ABCC4 mAb against human ABCC4 recombinant protein. (Expected MW is 32.4 kDa)
Figure 2: Western blot analysis using ABCC4 mAb against HEK293 (1) and ABCC4 (AA: 631-692)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Flow cytometric analysis of A549 cells using ABCC4 mouse mAb (green) and negative control (red).
Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ABCC4 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using ABCC4 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. |
|References (references)||1. Biochem Pharmacol. 2012 Aug 1;84(3):366-73. |
2. Arch Dermatol Res. 2012 Jan;304(1):57-63.