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Illustration of CAR construct
Figure 1: CAR-T cells expressing the above constructs are available from Promab targeting Mesothelin antigen. ScFv, single chain variable fragment
The Mesothelin scFv-TM28-CD28-CD3z, Mesothelin scFv-TM8-4-1BB-CD3z, and Mesothelin scFv-TM28-4-1BB-CD3z with CD3z control CAR-T cells are available at 1x107-1x109 cells in frozen vials and shipped on dry-ice. The Control Delta CD3 z CAR-T cells were cryopreserved in the next-generation cryopreservation CS10 CryoStor medium (Sigma Aldrich, Catalog Number: C2874. CryoStor is a registered trademark of BioLife Solutions, Inc.). All our cells are pathogen- and mycoplasma free.