EGFRscFv-4-1BB-CD3z

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ProMab's PM-CAR1022 primary human CAR-T cells express an anti-EGFR CAR containing an EGFR-specific scFv, hinge and transmembrane domains, the 4-1BB costimulatory domain and the CD3zeta activation domain.

 

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-80°C; liquid nitrogen
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Bioassay measuring cell count of target cells in the presence or absence of effector cells.
Figure 2: Real-time cytotoxicity assay (RTCA) with BxPC3 pancreatic cancer target cells and effector EGFRscFv-4-1BB-CD3ζ
Figure 2: Real-time cytotoxicity assay (RTCA) with BxPC3 pancreatic cancer target cells and effector EGFRscFv-4-1BB-CD3ζ
For Research Use Only. Not for use in diagnostic procedures.