CD138 CAR-T cells (CD138 scFv-FLAG-TM-CD28-CD3z)
CD138, encoded by the SDC1 gene, is a type I membrane proteoglycan expressed primarily by plasma cells. Also known as syndecan-1, CD138 links the cytoskeleton to the interstitial matrix.
ProMab's PM-CAR1028 primary human CAR-T cells express an anti-CD138 CAR containing a CD138-specific scFv, a FLAG tag, hinge and transmembrane domains, the CD28 costimulatory domain and the CD3zeta activation domain. The CAR-T cells are generated by transducing activated human T cells with replication-defective lentivirus encoding the CAR. After expansion, the cells are cryopreserved and shipped in vials containing up to 10 million cells. For orders over 10 million cells, please inquire. All ProMab cells are guaranteed to be sterile, pathogen-free and mycoplasma-free.